Boosting the power of genome-wide association studies within and across ancestries by using polygenic scores
Adrián I. Campos, Shinichi Namba, Shu‐Chin Lin, Kisung Nam, Julia Sidorenko, Huanwei Wang, Yoichiro Kamatani, The Biobank Japan Project, Ling-Hua Wang, Seunggeun Lee, Kuang Lin, Yen‐Chen Anne Feng, Yukinori Okada, Peter M. Visscher, Loïc Yengo
Topics & Concepts
Genome-wide association studyBiobankGenetic associationBiologyMeta-analysisStatistical powerComputational biologyPolygenic risk scoreGeneticsEvolutionary biologyDemographySingle-nucleotide polymorphismStatisticsGeneMedicineGenotypeInternal medicineMathematicsSociologyGenetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and AnimalsGenetic and phenotypic traits in livestock