Antimicrobial Resistance Gene Transfer from Campylobacter jejuni in Mono- and Dual-Species Biofilms
Luyao Ma, Michael E. Konkel, Xiaonan Lu
Abstract
0.05). Biofilm cultivation time and extracellular DNA (eDNA) amount were related to varied HGT frequencies. C. jejuni could spread AMR genes in both monospecies and dual-species biofilms, mimicking the survival mode of C. jejuni in food chains. These findings indicated that the risk and extent of AMR transmission among C. jejuni organisms have been underestimated, as previous HGT studies mainly focused on the planktonic state. Future AMR controlling measures can target biofilms and their main component eDNA.
Topics & Concepts
Campylobacter jejuniMicrobiologyBiofilmHorizontal gene transferBiologySalmonella entericaAntibiotic resistanceStrain (injury)CampylobacterGeneEscherichia coliBacteriaGeneticsAntibioticsPhylogeneticsAnatomySalmonella and Campylobacter epidemiologyBacterial biofilms and quorum sensingVibrio bacteria research studies