The effects of a 6-month intervention aimed to reduce sedentary time on skeletal muscle insulin sensitivity: a randomized controlled trial
Tanja Sjöros, Saara Laine, Taru Garthwaite, Henri Vähä‐Ypyä, Mikko Koivumäki, Olli Eskola, Eliisa Löyttyniemi, Noora Houttu, Kirsi Laitinen, Kari K. Kalliokoski, Harri Sievänen, Tommi Vasankari, Juhani Knuuti, Ilkka Heinonen
Abstract
Aiming to reduce daily SB by 1 h/day had no impact on skeletal muscle insulin sensitivity in the weight-bearing thigh muscles. However, successfully reducing SB may increase insulin sensitivity in the postural hamstring muscles. This emphasizes the importance of both reducing SB and increasing moderate-to-vigorous physical activity to improve insulin sensitivity in functionally different muscles of the body and thus induce a more comprehensive change in insulin sensitivity in the whole body.
Topics & Concepts
Insulin sensitivityInsulinSkeletal muscleMedicineHamstringInternal medicineRandomized controlled trialThighSensitivity (control systems)EndocrinologyPhysical medicine and rehabilitationInsulin resistanceSurgeryEngineeringElectronic engineeringPhysical Activity and HealthCardiovascular and exercise physiologyObesity, Physical Activity, Diet