Design, synthesis, and biological evaluation of 5-((8-methoxy-2-methylquinolin-4-yl)amino)-1H-indole-2-carbohydrazide derivatives as novel Nur77 modulators
Baicun Li, Jie Yao, Kaiqiang Guo, Fengming He, Kun Chen, Zongxin Lin, Shun-Zhi Liu, Jiangang Huang, Qiaoqiong Wu, Meijuan Fang, Jin-Zhang Zeng, Zhenhua Wu
Topics & Concepts
Nerve growth factor IBChemistryApoptosisEndoplasmic reticulumIn vivoCancer researchCell biologyBiochemistryBiologyTranscription factorNuclear receptorGeneBiotechnologyNuclear Receptors and SignalingSynthesis of Tetrazole DerivativesRNA Interference and Gene Delivery