mTOR-driven neural circuit changes initiate an epileptogenic cascade
Candi L. LaSarge, Raymund Y.K. Pun, Zhiqing Gu, Matthew Riccetti, Devi V. Namboodiri, Durgesh Tiwari, Christina Groß, Steve C. Danzer
Topics & Concepts
Hippocampal formationNeuroscienceExcitatory postsynaptic potentialPI3K/AKT/mTOR pathwayKnockout mouseBiologyPTENPhenotypeEpilepsyInhibitory postsynaptic potentialCell biologySignal transductionReceptorGeneticsGeneNeuroscience and Neuropharmacology ResearchRetinal Development and DisordersIon channel regulation and function