Human ucMSCs seeded in a decellularized kidney scaffold attenuate renal fibrosis by reducing epithelial–mesenchymal transition via the TGF-β/Smad signaling pathway
Dong Hu, Deying Zhang, Bo Liu, Yang Liu, Yu Zhou, Yihang Yu, Lianju Shen, Chunlan Long, Dan Zhang, Xing Liu, Tao Lin, Dawei He, Tao Xu, Peter Timashev, Denis Butnaru, Yuanyuan Zhang, Guanghui Wei, Yuanyuan Zhang, Guanghui Wei
Topics & Concepts
SMADEpithelial–mesenchymal transitionTransplantationDecellularizationFibrosisKidneyCancer researchTransforming growth factorMesenchymal stem cellMedicineExtracellular matrixPathologyCell biologyInternal medicineBiologyCancerMetastasisTissue Engineering and Regenerative MedicineRenal and related cancersMesenchymal stem cell research