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Ginsenoside CK targeting KEAP1-DGR/Kelch domain disrupts the binding between KEAP1 and NRF2-DLG motif to ameliorate oxidative stress damage

Chuanjing Cheng, Jinling Zhang, Kaixin Liu, Yanyan Xu, Fukui Shen, Yanqi Han, Yuanyuan Hou, Tiejun Zhang, Gang Bai

2023Phytomedicine27 citationsDOI

Topics & Concepts

KEAP1GinsengOxidative stressOxidative phosphorylationIn vivoDocking (animal)ChemistryBiochemistryCell biologyPharmacologyBiologyTranscription factorMedicinePathologyGeneGeneticsNursingAlternative medicineGinseng Biological Effects and ApplicationsGenomics, phytochemicals, and oxidative stressEndoplasmic Reticulum Stress and Disease
Ginsenoside CK targeting KEAP1-DGR/Kelch domain disrupts the binding between KEAP1 and NRF2-DLG motif to ameliorate oxidative stress damage | Litcius