Polyacetylenes from <i>Oplopanax horridus</i> and <i>Panax ginseng:</i> Relationship between Structure and PPARγ Activation
Mirta Rešetar, Xin Liu, Sonja Herdlinger, Olaf Kunert, Eva‐Maria Pferschy‐Wenzig, Simone Latkolik, Theresa Steinacher, Daniela Schuster, Rudolf Bauer, Verena M. Dirsch
Abstract
extracts. Additionally, they might guide the polyacetylene-based design of future PPARγ partial agonists.
Topics & Concepts
CytotoxicityStereochemistryChemistryGinsengIn silicoPeroxisome proliferator-activated receptorTranscription factorStructure–activity relationshipBiochemistryReceptorIn vitroGeneMedicineAlternative medicinePathologyPlant-derived Lignans Synthesis and BioactivityNatural product bioactivities and synthesisGenomics, phytochemicals, and oxidative stress