Biosynthesis of (MWCNTs)-COOH/CdO hybrid as an effective catalyst in the synthesis of pyrimidine-thione derivatives by water lily flower extract
Shahrbano Kaveh, Navabeh Nami, Banafsheh Norouzi, Ali Mirabi
Abstract
Pink Water lily flower, with the scientific name of Nymphaea alba in the family of Nymphaeaceae, was collected from North of Iran, Mazandaran in spring, dried in shade and powdered. The powdered flower material was extracted in 70% (vol/vol) ethanol. Acid functionalized multi-walled carbon nanotubes/CdO (MWCNTs-COOH/CdO) was fabricated by using the Water lily flower extract. The presence of CdO nanoparticles and their surface conjugation to MWCNT have been confirmed by FT-IR, X-ray diffraction, transmission electron microscopy, scanning electron microscopy and energy-dispersive X-ray spectroscopy. It was used as a highly efficient catalyst for the synthesis of some pyrazolo[3,4-d]pyrimidine and pyrido[2,3-d]pyrimidine derivatives. These compounds were synthesized by the reaction of some substituted pyrazole or pyridine, thiourea and I2 in the presence of MWCNTs-COOH/CdO hybrid (5% mol) in warm water. The assigned structure was further established by CHN analyses, NMR and FT-IR spectra.