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A new tau dephosphorylation-targeting chimera for the treatment of tauopathies

Jingfen Su, Yue Xiao, Linyu Wei, Huiyang Lei, Fei Sun, Weixia Wang, Shihong Li, Xiaochuan Wang, Jie Zheng, Jian‐Zhi Wang

2024Acta Pharmacologica Sinica15 citationsDOIOpen Access PDF

Topics & Concepts

Chimera (genetics)DephosphorylationMedicinePhosphorylationChemistryCell biologyBiologyBiochemistryPhosphataseGeneProtein Degradation and InhibitorsUbiquitin and proteasome pathwaysReceptor Mechanisms and Signaling
A new tau dephosphorylation-targeting chimera for the treatment of tauopathies | Litcius