Interactions between diabetes and COVID-19: A narrative review
Sophia Sabri, Olivier Bourron, Franck Phan, Lee S. Nguyen
Abstract
the alternate effects of the renin-angiotensin system, mediated by the angiotensin-converting-enzyme 2, was also associated with insulin resistance in key tissues involved in glucose homeostasis, such as liver, skeletal muscles, and adipose tissue; and also, with impaired insulin secretion by pancreatic β-cells. In this work, we reviewed all elements which may help understand how diabetes affects patients with COVID-19, how treatments affect outcomes in patients with COVID-19, how they may cause new onsets of diabetes, and finally review how SARS-CoV-2 may inherently be a risk factor of developing diabetes, through immune-mediated diabetogenic mechanisms.
Topics & Concepts
MedicineDiabetes mellitusInsulin resistanceEndothelial dysfunctionInternal medicinePneumoniaType 2 diabetesKidney diseaseSystemic inflammationDiseaseImmunologyInflammationEndocrinologyCOVID-19 Clinical Research StudiesDiabetes and associated disordersLong-Term Effects of COVID-19