Oxidative additions of alkynyl/vinyl iodides to gold and gold-catalyzed vinylation reactions triggered by the MeDalphos ligand
Jéssica Rodríguez, Alexis Tabey, Sonia Mallet‐Ladeira, Didier Bourissou
Abstract
tetrahydrofuranes, tetrahydropyranes, oxepanes and pyrrolidines were obtained thereby (24 examples, 87% average yield). Taking advantage of the chemoselectivity for vinyl iodides over aryl iodides, sequential transformations involving first a hetero-vinylation step and then a C-N coupling, a C-C coupling or an heteroarylation were achieved from a vinyl/aryl bis-iodide substrate.
Topics & Concepts
Oxidative additionChemistryCatalysisLigand (biochemistry)Oxidative phosphorylationCombinatorial chemistryOrganic chemistryPhotochemistryBiochemistryReceptorCatalytic Alkyne ReactionsCatalytic C–H Functionalization MethodsOxidative Organic Chemistry Reactions