Symmetric bis-benzimidazoles as DNA minor groove-binding agents with anti-tumour and antibacterial activity, and the evolution of the drug ridinilazole for the treatment of Clostridium difficile infections
Anne Baron, Christine Le Sann, John Mann
Topics & Concepts
Minor grooveChemistryClostridium difficileDNADrugClostridiumAntibacterial activityOligonucleotideAntibacterial agentMicrobiologyBiochemistryBacteriaAntibioticsPharmacologyBiologyGeneticsClostridium difficile and Clostridium perfringens researchAntibiotic Resistance in BacteriaCancer therapeutics and mechanisms