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A Broad Light‐Harvesting Conjugated Oligoelectrolyte Enables Photocatalytic Nitrogen Fixation in a Bacterial Biohybrid

Zhongxin Chen, Glenn Quek, Ji‐Yu Zhu, Samuel J. W. Chan, Sarah J. Cox‐Vázquez, Fernando López‐García, Guillermo C. Bazan

2023Angewandte Chemie International Edition36 citationsDOIOpen Access PDF

Abstract

Abstract We report a rationally designed membrane‐intercalating conjugated oligoelectrolyte (COE), namely COE‐IC , which endows aerobic N 2 ‐fixing bacteria Azotobacter vinelandii with a light‐harvesting ability that enables photosynthetic ammonia production. COE‐IC possesses an acceptor‐donor‐acceptor (A‐D‐A) type conjugated core, which promotes visible light absorption with a high molar extinction coefficient. Furthermore, COE‐IC spontaneously associates with A. vinelandii to form a biohybrid in which the COE is intercalated within the lipid bilayer membrane. In the presence of L‐ascorbate as a sacrificial electron donor, the resulting COE‐IC / A. vinelandii biohybrid showed a 2.4‐fold increase in light‐driven ammonia production, as compared to the control. Photoinduced enhancement of bacterial biomass and production of L‐amino acids is also observed. Introduction of isotopically enriched 15 N 2 atmosphere led to the enrichment of 15 N‐containing intracellular metabolites, consistent with the products being generated from atmospheric N 2 .

Topics & Concepts

PhotocatalysisNitrogen fixationConjugated systemNitrogenFixation (population genetics)Materials scienceNanotechnologyChemistryEnvironmental chemistryCatalysisOrganic chemistryPolymerBiochemistryComposite materialGeneMicrobial Fuel Cells and BioremediationAmmonia Synthesis and Nitrogen ReductionMicrobial Community Ecology and Physiology