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Precision Hydrogel Dressings Engineering for Wound Healing: Dual-Targeted Regulation of Cells and Microenvironment

Jianwei Zhang, Juan Song, Wanxue Zhao, Haoran Zhang, Xi Zhou, Haodong Liu, Shu Qin, Shibo Fu, Wenbo Li, Jianghong Zheng, Feng Guo, Cheng Chen

2025Engineered Science5 citationsDOIOpen Access PDF

Abstract

Wound healing is a highly coordinated and dynamic process encompassing four overlapping yet distinct stages: hemostasis, inflammation, proliferation, and remodeling, each characterized by unique microenvironments and cellular behaviors.Traditional hydrogel dressings often employ

Topics & Concepts

ChemistryBiomedical engineeringTissue engineeringSelf-healing hydrogelsCell biologyBiocompatible materialNanotechnologyImmune systemExtracellular matrixBiocompatibilityHydrogels: synthesis, properties, applicationsWound Healing and TreatmentsSilk-based biomaterials and applications