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De novo design of self-assembling peptides with antimicrobial activity guided by deep learning

Huayang Liu, Zilin Song, Yu Zhang, Bihan Wu, Dinghao Chen, Ziao Zhou, Hongyue Zhang, Sangshuang Li, Xinping Feng, Jing Huang, Huaimin Wang

2025Nature Materials85 citationsDOI

Topics & Concepts

Antimicrobial peptidesPeptideNanotechnologyMultiple drug resistanceAntimicrobialBiofilmIn vivoComputational biologyBacteriaBiologyChemistryCombinatorial chemistryMaterials scienceBiochemistryAntibioticsMicrobiologyBiotechnologyGeneticsAntimicrobial Peptides and ActivitiesSupramolecular Self-Assembly in MaterialsBacteriophages and microbial interactions
De novo design of self-assembling peptides with antimicrobial activity guided by deep learning | Litcius