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Metformin promotes the osseointegration of titanium implants under osteoporotic conditions by regulating BMSCs autophagy, and osteogenic differentiation

Lin Jiating, Rongyao Xu, Xiang Shen, Hongbing Jiang, Shuhu Du

2020Biochemical and Biophysical Research Communications40 citationsDOI

Topics & Concepts

OsseointegrationMetforminOsteocalcinRUNX2AutophagyAlkaline phosphataseImplantChemistryDentistryMedicineEndocrinologyInternal medicineSurgeryBiochemistryDiabetes mellitusApoptosisEnzymeBone health and treatmentsMesenchymal stem cell researchMetabolism, Diabetes, and Cancer
Metformin promotes the osseointegration of titanium implants under osteoporotic conditions by regulating BMSCs autophagy, and osteogenic differentiation | Litcius