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ESMO Clinical Practice Guideline interim update on the treatment of locally advanced oesophageal and oesophagogastric junction adenocarcinoma and metastatic squamous-cell carcinoma

Radka Obermannová, Trevor Leong

2025ESMO Open49 citationsDOIOpen Access PDF

Abstract

• This update provides recommendations for perioperative treatment of locally advanced oesophageal and OGJ adenocarcinoma. • Recent phase III data have demonstrated that perioperative ChT should be the preferred approach for most patients. • Updated recommendations are also provided for the use of immune checkpoint inhibitors in advanced squamous-cell carcinoma. • Algorithms for the management of locoregional oesophageal cancer and advanced squamous-cell carcinoma are provided. • Recommendations are based on available scientific data and the authors’ collective expert opinion.

Topics & Concepts

GuidelineMedicineInterimBasal cellOncologyInternal medicineAdenocarcinomaClinical PracticeGeneral surgeryCancerPathologyFamily medicineArchaeologyHistoryEsophageal Cancer Research and TreatmentGastric Cancer Management and OutcomesLung Cancer Treatments and Mutations
ESMO Clinical Practice Guideline interim update on the treatment of locally advanced oesophageal and oesophagogastric junction adenocarcinoma and metastatic squamous-cell carcinoma | Litcius