A novel bispecific antibody drug conjugate targeting HER2 and HER3 with potent therapeutic efficacy against breast cancer
Huifang Zong, Xi Li, Lei Han, Lei Wang, Junjun Liu, Yali Yue, Jie Chen, Yong Ke, Hua Jiang, Yueqing Xie, Baohong Zhang, Jianwei Zhu
Topics & Concepts
InternalizationAntibody-drug conjugateBreast cancerCancer researchMedicineIn vitroCancerConjugateAntibodyImmunotherapyCancer cellCancer immunotherapyPharmacologyMonoclonal antibodyChemistryImmunologyInternal medicineReceptorBiochemistryMathematicsMathematical analysisMonoclonal and Polyclonal Antibodies ResearchHER2/EGFR in Cancer ResearchGlycosylation and Glycoproteins Research