An AND-gate bioluminescent probe for precise tumor imaging
Chenchen Wang, Yajian Hong, Ling Dong, Cheng Hu, Duo Jin, Ronghua Zhao, Zian Yu, Yue Yuan
Abstract
An AND-gate bioluminescent probe FK-Luc-BH was constructed by integrating excitation-free BLI modality with a dual-locked strategy to monitor the co-localization of cathepsin L and hypochlorite in tumor sites for precise tumor imaging.
Topics & Concepts
BioluminescenceHypochloriteChemistryBiochemistryOrganic chemistryAdvanced biosensing and bioanalysis techniquesNanoplatforms for cancer theranosticsMolecular Sensors and Ion Detection