Fine particulate matter (PM2.5) promotes IgE-mediated mast cell activation through ROS/Gadd45b/JNK axis
Ying Wang, Ni Tang, Manyun Mao, Youyou Zhou, Yingfang Wu, Juan Li, Juan Li, Wei Zhang, Cong Peng, Xiang Chen, Jie Li, Jie Li
Topics & Concepts
DegranulationImmunoglobulin EMast cellChemistryReactive oxygen speciesProinflammatory cytokineGene knockdownCell biologyCytokineImmunologyInflammationBiologyApoptosisBiochemistryReceptorAntibodyMast cells and histamineAir Quality and Health ImpactsOccupational exposure and asthma