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Design, synthesis and molecular docking of 1,2,4-triazole schiff base hybrids as tubulin, EGFR inhibitors and apoptosis-inducers

Malik Suliman Mohamed, Nashwa A. Ibrahim, Ahmed M. Gouda, Mohamed Badr, Hany A.M. El-Sherief

2023Journal of Molecular Structure25 citationsDOI

Topics & Concepts

ChemistryDocking (animal)TriazoleTubulinIC50ApoptosisEGFR inhibitorsSchiff baseCell cycle checkpointCytotoxicityEpidermal growth factor receptorMicrotubuleStereochemistryCell cycleCombinatorial chemistryBiochemistryIn vitroReceptorCell biologyOrganic chemistryMedicineBiologyNursingSynthesis and biological activityClick Chemistry and ApplicationsSynthesis and Characterization of Heterocyclic Compounds
Design, synthesis and molecular docking of 1,2,4-triazole schiff base hybrids as tubulin, EGFR inhibitors and apoptosis-inducers | Litcius