Coding and Non-Coding RNAs, as Male Fertility and Infertility Biomarkers.
Fereshteh Aliakbari, Nahal Eshghifar, Reza Mirfakhraie, Parisa Pourghorban, Faezeh Azizi
Abstract
) in semen and testicular tissue. Thus, they might be used as predictor biomarkersto evaluate success rate of testicular sperm extraction (TESE) procedure, but confirmation of this hypothesis requires more extensive research. By comparing the number of RNAs attributed to each fertility disorder in men, it is possible to trace the causes of disease or return fertility to some infertile patients by regulating the mentioned molecules. Further researches can provide a better understanding of the use of RNA expression profiles in the diagnosis and treatment of male infertility.
Topics & Concepts
InfertilityFertilityCoding (social sciences)BiologyMale fertilityMale infertilityComputational biologyGeneticsGynecologyAndrologyMedicineStatisticsMathematicsPregnancyPopulationEnvironmental healthCancer-related molecular mechanisms researchGenetic and phenotypic traits in livestockMicroRNA in disease regulation