Design, synthesis, anti-inflammatory evaluation and molecular docking of novel thiophen-2-ylmethylene-based derivatives as potential TNF-α production inhibitors
Dina H. Dawood, Eman S. Nossier, Mohamed F. Abdelhameed, Gihan F. Asaad, Sahar S. Abd El‐Rahman
Topics & Concepts
CelecoxibChemistryPharmacologyAnti-inflammatoryAnalgesicPotencyIn vivoDocking (animal)Tumor necrosis factor alphaDrugIn vitroBiochemistryMedicineImmunologyBiotechnologyNursingBiologyInflammatory mediators and NSAID effectsSynthesis and biological activitySynthesis of β-Lactam Compounds