3D multi-cell-type liver organoids: A new model of non-alcoholic fatty liver disease for drug safety assessments
Julie Bronsard, Camille C. Savary, Julie Massart, R. Viel, Lucille Moutaux, Daniel Catheline, Vincent Rioux, Bruno Clément, Anne Corlu, Bernard Fromenty, Pierre‐Jean Ferron
Topics & Concepts
OrganoidFatty liverHepatic stellate cellSteatosisSteatohepatitisBiologyDrugDrug metabolismPhospholipidosisAdverse Outcome PathwayLiver injuryLiver cellToxicityPharmacologyPathologyMedicineInternal medicineBiochemistryCell biologyDiseaseEndocrinologyComputational biologyPhospholipidMembraneLiver physiology and pathologyLiver Disease Diagnosis and TreatmentDrug-Induced Hepatotoxicity and Protection