Increasing CRISPR Efficiency and Measuring Its Specificity in HSPCs Using a Clinically Relevant System
Jenny Shapiro, Ortal Iancu, Ashley M. Jacobi, Matthew McNeill, Rolf Turk, Garrett R. Rettig, Ido Amit, Adi Tovin-Recht, Zohar Yakhini, Mark A. Behlke, Ayal Hendel
Abstract
HSPCs for research and therapy and can be adapted for other hematopoietic cells.
Topics & Concepts
CRISPRComputational biologyBiologyComputer scienceGeneticsGeneCRISPR and Genetic EngineeringInnovation and Socioeconomic DevelopmentGenetics, Aging, and Longevity in Model Organisms