Low-dose aspirin inhibits trophoblast cell apoptosis by activating the CREB/Bcl-2 pathway in pre-eclampsia
Kai-Min Guo, Wei Li, Zhaohua Wang, Langchi He, Yan Feng, Huishu Liu
Abstract
: hydrogen peroxide; PBS: Phosphate-buffered saline; Bcl-2: B-cell lymphoma-2; MMP: Mitochondrial membrane potential; Cyt-c: CytochromeC.
Topics & Concepts
ApoptosisCREBBiologyTrophoblastTUNEL assayMolecular biologyCell biologyPlacentaBiochemistryTranscription factorPregnancyGeneticsGeneFetusPregnancy and preeclampsia studiesReproductive System and PregnancyMicroRNA in disease regulation