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Hemodynamic study in 3D printed stenotic coronary artery models: experimental validation and transient simulation

Violeta Carvalho, Nélson Rodrigues, Ricardo Ribeiro, Pedro F. Costa, José Carlos Teixeira, Rui Lima, Senhorinha Teixeira

2020Computer Methods in Biomechanics & Biomedical Engineering39 citationsDOI

Abstract

Atherosclerosis is a progressive disease that can significantly reduce blood supply to vital organs, being one of the main causes of death worldwide. In this work, a numerical and experimental study in 3D printed stenotic coronary arteries, considering both steady and pulsatile blood flow conditions, is presented. The results revealed that a degree of stenosis superior to 50% creates disturbed flows downstream of the contraction, with an accented increase in the wall shear stress measurements at the stenosis throat. Finally, the multiphase mixture was investigated and compared with a single-phase modelling, and only slight differences were observed right after the stenosis throat.

Topics & Concepts

Pulsatile flowStenosisCardiologyHemodynamicsInternal medicineShear stressBlood flowMedicineCoronary arteriesThroatArteryCoronary artery diseaseMaterials scienceAnatomyComposite materialCoronary Interventions and DiagnosticsCardiac Valve Diseases and TreatmentsRheology and Fluid Dynamics Studies
Hemodynamic study in 3D printed stenotic coronary artery models: experimental validation and transient simulation | Litcius