A dysfunctional TRPV4–GSK3β pathway prevents osteoarthritic chondrocytes from sensing changes in extracellular matrix viscoelasticity
Pranay Agarwal, Hong-Pyo Lee, Piera Smeriglio, Fiorella C. Grandi, Stuart B. Goodman, Ovijit Chaudhuri, Nidhi Bhutani
Topics & Concepts
TRPV4OsteoarthritisExtracellular matrixChondrocyteCell biologyExtracellularCartilageChemistryTransient receptor potential channelIntracellularSignal transductionMedicineBiologyReceptorBiochemistryAnatomyPathologyAlternative medicineOsteoarthritis Treatment and MechanismsVeterinary Equine Medical Research