A functional cardiac patch promotes cardiac repair by modulating the CCR2− cardiac-resident macrophage niche and their cell crosstalk
Chengbin Ding, Guofeng Tang, Yan Sun, Xiaodong Fu, Ye Tian, Jiamian Zhan, Songtao Zhang, Xianglong Xing, Jianing Liu, Xiaozhong Qiu, Leyu Wang
Abstract
transgenic lineage tracing mice. Overall, this study provides a promising strategy to construct a synergistic reparative microenvironment for MI repair.
Topics & Concepts
CrosstalkCardiac cellNicheCell biologyMacrophageMedicineBiologyPhysicsEcologyGeneticsIn vitroOpticsPeptidase Inhibition and AnalysisCardiac Fibrosis and RemodelingCardiac Structural Anomalies and Repair