Synthesis and antibiofilm activity of 1,2,3-triazole-pyridine hybrids against methicillin-resistant <i>Staphylococcus aureus</i> (MRSA)
Tamer El Malah, Hanan A. Soliman, Bahaa A. Hemdan, Randa E. Abdel Mageid, Hany F. Nour
Abstract
Antibiotic-resistant bacteria are emerging at an alarming rate, posing a potential threat to human health. A series of 1,2,3-triazole-pyridine hybrids were synthesised as promising antibiofilm agents against planktonic and sessile MRSA.
Topics & Concepts
ChemistryStaphylococcus aureusMethicillin-resistant Staphylococcus aureusPyridineTriazoleMicrobiologyAntimicrobialBacteriaCombinatorial chemistryOrganic chemistryGeneticsBiologyClick Chemistry and ApplicationsSynthesis and Biological EvaluationChemical Synthesis and Analysis