In-vitro anticancer evaluation of newly designed and characterized tri/tetra-substituted imidazole congeners- maternal embryonic leucine zipper kinase inhibitors: Molecular docking and MD simulation approaches
Monalisa Mahapatra, Priyanka Mohapatra, Kakarla Pakeeraiah, Ravi Kumar Bandaru, Iqrar Ahmad, Suvadeep Mal, Rambabu Dandela, Sanjeeb Kumar Sahoo, Harun Patel, Sudhir Kumar Paidesetty
Topics & Concepts
Docking (animal)ImidazoleChemistryIn silicoIn vitroStereochemistryLeucine zipperCell cultureBiochemistryBiologyPeptide sequenceGeneNursingMedicineGeneticsCancer Mechanisms and TherapySynthesis and biological activityFOXO transcription factor regulation