A Method for Producing Highly Pure Magnetosomes in Large Quantity for Medical Applications Using Magnetospirillum gryphiswaldense MSR-1 Magnetotactic Bacteria Amplified in Minimal Growth Media
Clément Berny, Raphaël Le Fèvre, François Guyot, Karine Blondeau, Christine Guizonne, Emilie Rousseau, Nicolas Bayan, Edouard Alphandéry
Abstract
of ~8 and 10 mg of magnetosomes in iron per liter of growth media. Compared with magnetosomes produced in non-minimal growth media, those particles have lower concentrations in metals other than iron. Very significant reduction or disappearance in magnetosome composition of zinc, manganese, barium, and aluminum are observed. This new synthesis method paves the way towards the production of magnetosomes for medical applications.
Topics & Concepts
MagnetosomeMagnetotactic bacteriaBacteriaManganeseChemistryMicrobiologyBiologyGeneticsOrganic chemistryGeomagnetism and Paleomagnetism StudiesMagnetic and Electromagnetic EffectsGeochemistry and Elemental Analysis