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Serine synthesis sustains macrophage IL-1β production via NAD+-dependent protein acetylation

Chuanlong Wang, Qingyi Chen, Siyuan Chen, Lijuan Fan, Zhending Gan, Muyang Zhao, Lexuan Shi, Bin Peng, Guan Yang, Xihong Zhou, Wenkai Ren

2024Molecular Cell76 citationsDOIOpen Access PDF

Topics & Concepts

BiologyNAD+ kinaseSerineAcetylationInflammationCell biologyInflammasomeInnate immune systemReceptorBiochemistryEnzymeImmunologyPhosphorylationGeneImmune cells in cancerInflammasome and immune disordersImmune Response and Inflammation
Serine synthesis sustains macrophage IL-1β production via NAD+-dependent protein acetylation | Litcius