Synthesis, anti-inflammatory effects, molecular docking and molecular dynamics studies of 4-hydroxy coumarin derivatives as inhibitors of COX-II enzyme
Dunya AL-Duhaidahawi, Haider F. S. Al-Zubaidy, Khattab Al-Khafaji, Ahmed A. Al‐Amiery
Topics & Concepts
ChemistryCoumarinPharmacologyIn silicoEnzymeToxicityAnti-inflammatoryCarrageenanDocking (animal)Acute toxicityInflammationEdemaStereochemistryBiochemistryOrganic chemistryInternal medicineNursingMedicineGeneSynthesis and biological activityFree Radicals and AntioxidantsBioactive Compounds and Antitumor Agents