Comparison of celecoxib and acetaminophen for pain relief in pediatric day case tonsillectomy: A randomized double‐blind study
Mohammad Faramarzi, Sareh Roosta, Mohammad Hossein Eghbal, Bahar Noori‐Rahmatabadi, Ali Faramarzi, Soliman Mohammadi‐Samani, Mahmood Shishegar, Mohammad Ali Sahmeddini
Abstract
OBJECTIVE: Post-tonsillectomy pain is a common morbidity in children. The aim of this study was to compare the efficacy of celecoxib with acetaminophen on pain relief in pediatric day-case tonsillectomy. METHODS: We compared the analgesic effect of celecoxib (99 patients) with acetaminophen (100 patients) for the management of post-tonsillectomy pain. Post-tonsillectomy pain score was evaluated three times a day for 7 days. In addition, the incidence of post-tonsillectomy bleeding and the rate of patients who returned to regular diet were evaluated. RESULTS: = 0.013). The overall pain score in other days was not significantly different between the two groups. In the celecoxib group, more patients resumed regular amount of oral intake within the first 3 days. Also, the rate of post-tonsillectomy bleeding in the two groups was not statistically different. CONCLUSION: We recommend celecoxib as a more suitable choice than acetaminophen for post-tonsillectomy pain management in the first day and resuming regular diet within 3 days.Level of Evidence: 1b.