DNA repair pathway activation features in follicular and papillary thyroid tumors, interrogated using 95 experimental RNA sequencing profiles
Uliana Vladimirova, P. O. Rumyantsev, Marianna Zolotovskaia, Eugene Albert, A.T. Abrosimov, K. Yu. Slashchuk, П. А. Никифорович, Olga S. Chukhacheva, Нуршат Гайфуллин, Maria Suntsova, Г. С. Захарова, Alexander Glusker, Daniil Nikitin, Andrew Garazha, Xinmin Li, Dmitriy E. Kamashev, Alexei L. Drobyshev, Irina Kochergina-Nikitskaya, Maxim Sorokin, Anton Buzdin
Abstract
) for the radioactive iodine resistant tumor. The differences in DNA repair activation patterns may help to improve therapy of different thyroid cancer types under investigation and the data communicated may serve for finding additional markers of radioiodine resistance.
Topics & Concepts
Cancer researchThyroid cancerFollicular thyroid cancerPapillary thyroid cancerBiologyThyroidCancerFusion geneGenePathologyMedicineGeneticsThyroid Cancer Diagnosis and TreatmentCancer-related Molecular PathwaysGenetic factors in colorectal cancer