Synthesis, characterization and cytotoxic activity studies on cancer cell lines of new paraben-decorated monospiro-cyclotriphosphazenes
Elif Şenkuytu, Nadide Akbaş, Tuba Yıldırım, Gönül Yenilmez Çiftçi
Abstract
Cancer is one of the leading causes of death worldwide. In this study, monospiro-cyclotriphosphazene compounds decorated with different parabens that likely show biological activity were designed and successfully synthesized for the first time.
Topics & Concepts
ChemistryParabenCytotoxic T cellCancer cell linesCancerCharacterization (materials science)CytotoxicityCancer cellNanotechnologyBiochemistryOrganic chemistryInternal medicineIn vitroPreservativeMedicineMaterials scienceFlame retardant materials and propertiesSynthesis of Organic CompoundsOrganophosphorus compounds synthesis