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Reprogramming of macrophages with macrophage cell membrane-derived nanoghosts

Jangsun Hwang, Mengjia Zheng, Christian Wiraja, Mingyue Cui, Lixia Yang, Chenjie Xu

2020Nanoscale Advances28 citationsDOIOpen Access PDF

Abstract

cytokine analysis and immunostaining of the nanoghost-treated cells. We find that several cytokines/chemokines are highly expressed on nanoghosts. In addition, a 2D wound healing model is deployed to reveal their potential application in clinical settings.

Topics & Concepts

ReprogrammingMacrophageImmunostainingChemokineCell biologyCytokineCellMacrophage inflammatory proteinPhenotypeInflammationChemistryImmunologyBiologyIn vitroImmunohistochemistryGeneBiochemistryImmune cells in cancerExtracellular vesicles in diseaseNanoplatforms for cancer theranostics
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