A next generation mathematical model for the in vitro to clinical translation of T-cell engagers
David Flowers, David M. Bassen, Georgi I. Kapitanov, Diana H. Marcantonio, John M. Burke, Joshua F. Apgar, Alison Betts, Fei Hua
Topics & Concepts
AvidityTrimerIn vitroTranslation (biology)ChemistryIn vivoCytotoxicityT cellComputational biologyCell biologyCD8AntigenBiophysicsComputer scienceCancer researchImmune systemImmunologyBiologyBiochemistryGeneticsMessenger RNAOrganic chemistryGeneDimerCAR-T cell therapy researchMonoclonal and Polyclonal Antibodies ResearchImmune Cell Function and Interaction