Synthesis of and anti-fibrotic effect of pyrazole derivative J-1048: Inhibition of ALK5 as a novel approach to liver fibrosis targeting inflammation
Hongxu Yang, Fang-Yan Guo, Yong-Ce Lin, Yan‐Ling Wu, Ji‐Xing Nan, Cheng Hua Jin, Li‐Hua Lian
Topics & Concepts
ChemistryPharmacologyFibrosisThioacetamideInflammationHepatic stellate cellCancer researchMedicineImmunologyBiochemistryInternal medicineLiver physiology and pathologyTGF-β signaling in diseasesLiver Disease Diagnosis and Treatment