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Determinants for intrinsically disordered protein recruitment into phase-separated protein condensates

Yongsang Jo, Jin‐Young Jang, Daesun Song, Hyoin Park, Yongwon Jung

2021Chemical Science34 citationsDOIOpen Access PDF

Abstract

∼ 5 μM) were substantially stronger than those by natural IDP-IDP interactions. The present data offer valuable information on how cells might organize protein partitioning on various protein condensates.

Topics & Concepts

Intrinsically disordered proteinsPhase (matter)Chemical physicsChemistryBiophysicsBiologyOrganic chemistryRNA Research and SplicingProtein Structure and DynamicsRNA and protein synthesis mechanisms
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