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Inhibition of Microglial NLRP3 with MCC950 Attenuates Microglial Morphology and NLRP3/Caspase-1/IL-1β Signaling In Stress-induced Mice

Qing Liu, Manman Zhang, Min-Xia Guo, Qiuping Zhang, Na-Zhi Li, Jie Cheng, Shi-Le Wang, Guang‐Hui Xu, Cheng‐Fu Li, Ji‐Xiao Zhu, Li‐Tao Yi

2022Journal of Neuroimmune Pharmacology49 citationsDOI

Topics & Concepts

NeuroinflammationMicrogliaInflammasomePrefrontal cortexProinflammatory cytokineCaspase 1PharmacologyChemistryNeuroscienceCell biologyReceptorInternal medicineMedicineInflammationPsychologyBiologyCognitionTryptophan and brain disordersNeuroinflammation and Neurodegeneration MechanismsInflammasome and immune disorders
Inhibition of Microglial NLRP3 with MCC950 Attenuates Microglial Morphology and NLRP3/Caspase-1/IL-1β Signaling In Stress-induced Mice | Litcius