<p>BK Virus Nephropathy: Prevalence, Impact and Management Strategies</p>
Rajeev Sharma, Mareena Zachariah
Abstract
Abstract: BK virus reactivation as a result of therapeutic immunosuppression following renal transplant can result in BK polyomavirus nephropathy and renal allograft loss. This is a complex and challenging clinical problem with a range of management options and practices reported in literature. The current standard for early diagnosis and treatment is surveillance by measuring viral DNA in blood using qPCR. Immunosuppression reduction is the cornerstone of effective management but is associated with a risk of acute rejection following treatment. Keywords: BK polyomavirus nephropathy, kidney transplant, immune monitoring, treatment, surveillance
Topics & Concepts
MedicineBK virusInternal medicineNephropathyPediatricsUrologyEndocrinologyDiabetes mellitusPolyomavirus and related diseases