SREBP-1c impairs ULK1 sulfhydration-mediated autophagic flux to promote hepatic steatosis in high-fat-diet-fed mice
Thuy T. P. Nguyen, Do Young Kim, Yu-Geon Lee, Young-Seung Lee, Xuan T. Truong, Jae‐Ho Lee, Dae‐Kyu Song, Taeg Kyu Kwon, So‐Hyun Park, Chang Hwa Jung, Changjong Moon, Timothy F. Osborne, Seung‐Soon Im, Tae–Il Jeon
Topics & Concepts
BiologyAutophagySteatosisULK1Flux (metallurgy)EndocrinologyInternal medicineFatty liverCell biologyBiochemistryAMPKKinaseProtein kinase AMedicineDiseaseMaterials scienceMetallurgyApoptosisLiver Disease Diagnosis and TreatmentDiet, Metabolism, and DiseasePancreatic function and diabetes