An all-in-one biomimetic iron-small interfering RNA nanoplatform induces ferroptosis for cancer therapy
Siming Huang, Hongbo Le, Guobin Hong, Guosheng Chen, Fang Zhang, Liejing Lu, Xiang Zhang, Ya Qiu, Zhe Wang, Qinyuan Zhang, Gangfeng Ouyang, Jun Shen
Topics & Concepts
GlutathioneGPX4Cancer cellSmall interfering RNAReactive oxygen speciesCancer researchLipid peroxidationChemistryIntracellularCancerAntioxidantGlutathione peroxidaseMaterials scienceBiochemistryBiologyTransfectionEnzymeGeneticsGeneFerroptosis and cancer prognosisNanoplatforms for cancer theranosticsRNA modifications and cancer