Heat stress induces RIP1/RIP3-dependent necroptosis through the MAPK, NF-κB, and c-Jun signaling pathways in pulmonary vascular endothelial cells
Wei Huang, Weidang Xie, Jian Ping Gong, Wenyan Wang, Sumin Cai, Qiaobing Huang, Zhongqing Chen, Yanan Liu
Topics & Concepts
NecroptosisHMGB1Cell biologyMAPK/ERK pathwaySignal transductionNF-κBKinaseDownregulation and upregulationChemistryBiologyGene knockdownMolecular biologyCancer researchProgrammed cell deathReceptorApoptosisBiochemistryGeneThermoregulation and physiological responsesClimate Change and Health ImpactsHeat shock proteins research