GID E3 ligase supramolecular chelate assembly configures multipronged ubiquitin targeting of an oligomeric metabolic enzyme
Dawafuti Sherpa, Jakub Chrustowicz, Shuai Qiao, Christine Langlois, Laura Hehl, Karthik V Gottemukkala, Fynn M. Hansen, Özge Karayel, Susanne von Gronau, J. Rajan Prabu, Matthias Mann, Arno F. Alpi, Brenda A. Schulman
Topics & Concepts
Ubiquitin ligaseAllosteric regulationBiologyUbiquitin-Protein LigasesDNA ligaseUbiquitinBiochemistrySupramolecular chemistrySupramolecular assemblyEnzymeSubstrate (aquarium)Plasma protein bindingCell biologyBiophysicsChemistryCrystallographyEcologyCrystal structureGeneUbiquitin and proteasome pathwaysRNA modifications and cancerBiochemical and Molecular Research