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Mitochondrial dysfunction caused by outer membrane vesicles from Gram-negative bacteria activates intrinsic apoptosis and inflammation

Pankaj Deo, Seong Hoong Chow, Mei‐Ling Han, Mary Speir, Cheng Huang, Ralf B. Schittenhelm, Subhash Dhital, Jack Emery, Jian Li, Benjamin T. Kile, James E. Vince, Kate E. Lawlor, Thomas Naderer

2020Nature Microbiology234 citationsDOI

Topics & Concepts

InflammasomeBacterial outer membranePyroptosisCell biologyInnate immune systemBiologyMitochondrionApoptosisMicrobiologyInflammationImmune systemEscherichia coliImmunologyBiochemistryGeneInflammasome and immune disordersBacterial Infections and VaccinesAmoebic Infections and Treatments
Mitochondrial dysfunction caused by outer membrane vesicles from Gram-negative bacteria activates intrinsic apoptosis and inflammation | Litcius