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DeepCOVIDExplainer: Explainable COVID-19 Diagnosis from Chest X-ray Images

Md. Rezaul Karim, Till Döhmen, Michael Cochez, Oya Beyan, Dietrich Rebholz‐Schuhmann, Stefan Decker

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Abstract

In this paper <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">1</sup> , we proposed an explainable deep neural networks (DNN)-based method for automatic detection of COVID-19 symptoms from chest radiography (CXR) images, which we call ‘DeepCOVIDExplainer’. We used 15,959 CXR images of 15,854 patients, covering normal, pneumonia, and COVID-19 cases. CXR images are first comprehensively preprocessed and augmented before classifying with a neural ensemble method, followed by highlighting class-discriminating regions using gradient-guided class activation maps (Grad-CAM ++) and layer-wise relevance propagation (LRP). Further, we provide human-interpretable explanations for the diagnosis. Evaluation results show that our approach can identify COVID-19 cases with a positive predictive value (PPV) of 91.6%, 92.45%, and 96.12%, respectively for normal, pneumonia, and COVID-19 cases, respectively, outperforming recent approaches. <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">1</sup> Read longer version of this paper: https://arxiv.org/pdf/2004.04582.pdf

Topics & Concepts

Coronavirus disease 2019 (COVID-19)Artificial intelligenceSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Pneumonia2019-20 coronavirus outbreakClass (philosophy)Computer scienceArtificial neural networkImage (mathematics)Pattern recognition (psychology)MedicinePathologyInternal medicineInfectious disease (medical specialty)DiseaseOutbreakCOVID-19 diagnosis using AIMachine Learning in HealthcareAnomaly Detection Techniques and Applications
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